MPSC Assistant Chemical Analyser Syllabus 2026 – Group-B Exam Pattern

MPSC Assistant Chemical Analyser Syllabus Exam Syllabus & Pattern 2026

The Maharashtra Public Service Commission (MPSC) has officially released the detailed syllabus for the post of Assistant Chemical Analyser under the Directorate of Forensic Science Laboratories (DFSL), General State Services, Group-B, Home Department, Government of Maharashtra. This comprehensive guide provides a complete breakdown of the syllabus, exam pattern, and preparation strategies to help aspirants crack the examination with confidence. The syllabus is meticulously designed to test candidates' knowledge in analytical chemistry and its applications in forensic science, covering four major units: Analytical Chemistry, Inorganic Chemistry Techniques, Organic Chemistry Techniques, and Biochemistry Techniques.

About MPSC Assistant Chemical Analyser Written Exam

The MPSC Assistant Chemical Analyser examination is a competitive recruitment process conducted by the Maharashtra Public Service Commission to select qualified candidates for the post of Assistant Chemical Analyser in the Directorate of Forensic Science Laboratories (DFSL), Maharashtra. This Group-B post falls under the General State Services and is crucial for forensic analysis and scientific investigation. The written exam is designed to assess the candidate's proficiency in various branches of chemistry, with a strong emphasis on analytical techniques used in forensic laboratories. The exam pattern includes a single paper of 200 marks, comprising 100 objective-type questions to be answered within one hour. Candidates who clear the written examination are shortlisted for further selection stages, which may include document verification and interview.

MPSC Assistant Chemical Analyser Syllabus Exam Scheme & Marking

Understanding the exam pattern is essential for effective preparation. The MPSC Assistant Chemical Analyser exam follows a structured scheme, as detailed in the table below. Candidates should note that the exam is conducted in offline mode (pen-paper based) and consists of objective-type multiple-choice questions. Each question carries two marks, and there is no negative marking as per the official notification. The total duration is 60 minutes, making time management a critical factor for success.

Detailed Subject-Wise Syllabus

The MPSC Assistant Chemical Analyser syllabus is divided into four major units, each focusing on a specific domain of chemistry. Candidates must thoroughly prepare each unit, as questions are drawn from all sections. Below is a detailed topic-wise breakdown of the syllabus.

1. Analytical Chemistry

(A) Basic Aspects

• Sampling of solid, liquid, and gas samples
• Molecular and equivalent weight
• Molarity, molality, normality
• Solution preparation in w/w, w/v, and v/v terms
• Mole concept, concentrations, ppm, ppb, and ppt
• Calibration and validation: calibration curve, regression analysis, external standard, internal standard, and standard addition method

(B) Statistical Treatment of Results

• Accuracy, precision, sensitivity, detection limit
• Errors and their types, mean, median, standard deviation, relative standard deviation
• Gaussian curve, t-test, F-test, confidence interval
• Criteria for selection of analytical methods: accuracy, precision, sensitivity, selectivity, specificity, detection limit

(C) Titrimetry

• Types of titrations: acid-base, complexometric, redox, precipitation
• Standards used for standardisation: primary standard and secondary standard
• Potentiometric and conductometric titration and their applications

(D) Gravimetric and Thermogravimetric Analysis

• Precipitation and different precipitants used in gravimetric analysis
• pH requirement for precipitation
• Quantitative analysis
• Thermogravimetric analysis
• Mass spectrometry for qualitative and quantitative analysis, and related problems

(E) Separation Techniques

• Extraction methods
• Distillation methods: vacuum distillation, steam distillation, fractional distillation
• Purification and identification of substances

2. Analytical Techniques in Inorganic Chemistry for Different Inorganic Samples

(A) Spectroscopy and Chromatography for Inorganic Sample Analysis

• Atomic absorption, atomic emission, and inductively coupled plasma-atomic emission and mass spectrometry (ICP-AES and ICP-MS)
• UV-Visible spectroscopy for qualitative and quantitative analysis, Job's Method, and applications
• Ion exchange chromatography for analysis of various inorganic cations and anions

(B) Microscopy for Inorganic Sample Analysis

• Trace and heavy metal, glass, soil, and liquid sample analysis using Scanning Electron Microscopy (SEM)
• Energy Dispersive Spectroscopy (EDS)

(C) Electroanalytical Techniques

• Coulometry and its types
• Amperometry, voltammetry, cyclic voltammetry, stripping voltammetry
• Polarography

3. Analytical Techniques in Organic Chemistry

(A) Spectroscopy

• Theory and application of UV-Visible, IR (FTIR), Raman, NMR, and Mass spectrometry
• Interpretation of spectra and structure elucidation

(B) Separation Techniques

• Theory and application in chemical analysis of TLC, HPTLC, GC, GC-MS, LC-MS, HRMS, column chromatography, and paper chromatography
• HPLC: ion exchange chromatography, adsorption chromatography, normal and reverse phase chromatography, solid phase extraction

(C) Organic Analysis

• Pharmaceutical and narcotic drugs, psychotropic substances
• Alcohol estimation
• Petroleum products, paints and dyes, rubber, plastic, fibres
• Organic poisons such as insecticides, pesticides, herbicides, etc.

4. Analytical Techniques in Biochemistry

(A) Biomolecules

• Structure, functions, and estimation of carbohydrates, lipids, proteins, nucleic acids
• Biological buffers

(B) Molecular Biology

• DNA isolation, DNA quantification
• PCR, RT-PCR, RFLP (Restriction Fragment Length Polymorphism)
• ELISA, RIA (Radio Immuno Assay)
• Antigen-antibody reactions

(C) Separation Techniques

• SDS-PAGE, one dimension (PAGE) and two dimension electrophoresis
• Isoelectric focusing
• Gel filtration chromatography, affinity chromatography
• High voltage electrophoresis, agarose electrophoresis, capillary electrophoresis

(D) Isotope Tracer Technique

• Basic concepts and principles
• Advantages, limitations, and applications in biochemistry

(E) Enzymes

• Enzyme classification, isoenzymes
• DNA polymerase
• Enzyme kinetics (basic)

(F) Blood and Other Body Fluid and Hair Examination (Human and Animal)

• Blood group system
• Semen examination, saliva, urine, hair, sweat
• Biological stains and their preservation

MPSC Assistant Chemical Analyser Syllabus Selection Stages

The selection process for the MPSC Assistant Chemical Analyser post typically involves multiple stages. While the official notification may specify the exact stages, the general selection procedure includes:

• Written Examination: A single paper of 200 marks, consisting of 100 objective-type questions covering the entire syllabus.
• Document Verification: Candidates who qualify in the written exam are called for verification of their educational certificates, age proof, caste certificates (if applicable), and other relevant documents.
• Interview (if applicable): Depending on the recruitment rules, a personal interview may be conducted to assess the candidate's suitability for the post.

Candidates are advised to refer to the official notification for the exact selection procedure, as it may vary.

Preparation Strategy & Tips

To excel in the MPSC Assistant Chemical Analyser exam, a well-planned preparation strategy is essential. Here are some expert tips to help you prepare effectively:

• Understand the Syllabus Thoroughly: Go through the entire syllabus and make a checklist of topics. Prioritize areas where you are weak and allocate more time to them.
• Build a Study Schedule: Create a daily or weekly timetable that covers all four units. Dedicate extra time to Analytical Chemistry and Organic Chemistry techniques, as they form the core of the exam.
• Focus on Instrumental Techniques: Pay special attention to spectroscopy and chromatography techniques such as ICP-MS, GC-MS, HPLC, and SEM-EDS. Understand their principles, applications, and interpretations.
• Practice Statistical Problems: Topics like t-test, F-test, standard deviation, and confidence interval are calculation-based. Practice these regularly to gain accuracy and speed.
• Make Short Notes: Create concise notes for each topic, especially for separation techniques and biochemical methods. These will be handy for quick revision.
• Solve Previous Year Papers: If available, solve previous year question papers of similar exams to understand the pattern and difficulty level. This will also help in time management.
• Stay Updated: Regularly check the official MPSC website for any updates regarding the exam date, pattern changes, or additional instructions.

Official Syllabus PDF Link

For your convenience, we have provided the direct links to download the official syllabus PDF and other important resources. Candidates are advised to download the syllabus from the official website to ensure authenticity.

Note: The above links are provided for reference. Always verify the official website for the most accurate and updated information.

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